Genetic Disorders Mini Project: Working with a partner (one from Biology and one from Health, if possible), choose one disease and, based on the pattern of inheritance, draw a Punnett square and a pedigree and write your predictions about how this disease passes from generation to generation.
The human genome contains an estimated total of 20,000-25,000 genes that serve as blueprints for building all of our proteins (International Human Genome Sequencing Consortium, 2004). In single-gene diseases, a mutation in just one of these genes is responsible for disease. Single-gene diseases run in families and can be dominant or recessive, and autosomal or sex-linked. Pedigree analyses of large families with many affected members are very useful for determining the inheritance pattern of single-gene diseases.
Mini Project: Working with a partner (one from Biology and one from Health, if possible), choose one disease and, based on the pattern of inheritance, draw a Punnett square and a pedigree and write your predictions about how this disease passes from generation to generation.
The human genome contains an estimated total of 20,000-25,000 genes that serve as blueprints for building all of our proteins (International Human Genome Sequencing Consortium, 2004). In single-gene diseases, a mutation in just one of these genes is responsible for disease. Single-gene diseases run in families and can be dominant or recessive, and autosomal or sex-linked. Pedigree analyses of large families with many affected members are very useful for determining the inheritance pattern of single-gene diseases.
Homework: 1) Check this out: The top 10 most unusual genetic disorders
2) RESPECTFULLY comment on this blog to this post:
"Imagine someone in your family has one of these disorders. How would you handle it?"